Metal complex strategies for photo-uncaging the small molecule bioregulators nitric oxide and carbon monoxide
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چکیده
منابع مشابه
Novel small molecule therapeutics for sickle cell disease: nitric oxide, carbon monoxide, nitrite, and apolipoprotein A-I.
A hemolysis-linked subphenotype of sickle cell disease (SCD), characterized by pulmonary hypertension, stroke, priapism and leg ulcers, is associated with decreased nitric oxide bioavailability and vasculopathy. Vasculopathy appears to have a multifactorial etiology, including mechanisms primarily that involve deficient nitric oxide (NO) signaling, but also involving altered function of NO synt...
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Carbon monoxide (CO) and nitric oxide (NO) can be involved in the regulation of cerebral circulation. Inhibition of production of either one of these gaseous intercellular messengers inhibits newborn pig cerebral arteriolar dilation to the excitatory amino acid glutamate. Glutamate can increase NO production. Therefore, the present study tests the hypothesis that NO, which is increased by gluta...
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The reduction of nitric oxide by carbon monoxide, reaction (l), mediated by metal complexes has attracted great attention recently due to its relevance to the control of air pollution and the intrinsic interest in the mechanism of N20 and C02 formation. 1-7 While a number of catalyst systems for reaction (1) have been reported, only the RhIILRhI and the PdC12CuCI2. systems rapidly catalyse the ...
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ژورنال
عنوان ژورنال: Coordination Chemistry Reviews
سال: 2018
ISSN: 0010-8545
DOI: 10.1016/j.ccr.2018.07.018